AOTF‑NIR for Quality & Process Control

Brimrose AOTF-NIR spectroscopy is a technique that has gained widespread acceptance as a powerful diagnostic tool, particularly for quality assurance and process analytical control (PAT) purposes in pharmaceutical, food/agricultural, and chemical industries. NIR has been in use in the pharmaceutical industry even before PAT initiative was introduced in the early 2000’s. The initial use for NIR was for raw material identification to reduce the costs and time of laboratory testing. Below is a selection of real‑time applications supported by our AOTF-NIR technology. For more applications, please contact us.

Blending Uniformity

Brimrose’s solid‑state AOTF module and vibration‑resistant optical design enable enable our spectrometers to be integrated directly into the blender, providing continuous, real‑time monitoring of blend progression. Our spectrometers determine when blending is complete, minimizing production time, and cost to market of your products.

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Reaction Monitoring

Brimrose solid state AOTF module with rugged, no‑moving‑parts optical design enable our spectrometers to be integrated directly into the reactor for real-time measurement. By tracking reaction progress in-process, our spectrometers identify the precise point at which the reaction reaches completion. This real‑time endpoint determination minimizes production delays and lowers the cost of bringing your products to market.

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FBD Drying Processing

Brimrose spectrometers are the perfect tools for in-line continuous monitoring of Fluidized Bed Dryers and Lyophilization. Mounted directly onto the dryer, Brimrose spectrometers determine the moisture during every step in the drying process for each batch; preventing product waste and improving turnaround time. As opposed to traditional methods, FBD offers faster dry times with uniform drying conditions. If properly implemented, FBD provides an ideal solution for the gentle drying of your products.

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Tablet Coating Analysis

AOTF-NIR spectroscopy is a non-destructive, rapid test method. The technique has been proven to accurately measure the presence and uniformity of coating on light and dark tablets, and is commonly used by pharmaceutical companies for this purpose. Brimrose AOTF-NIR has a distinct advantage over other spectroscopy devices due to its very fast scanning speed. Our AOTF-NIR technology has been proven to work up to 60,000 tablets per hour.

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Sorting Seeds & Peanuts

Brimrose Spectrometers give breeders the ability to selectively discriminate, qualify, and sort seeds for the most desired qualities. Brimrose offers true single seed analysis enabling thousands of samples to be tested with minimal cost or time consumption. The SEEDMEISTER Mark IIIx is an accurate, repeatable, and low-cost solution for sorting peanuts. Models have been developed for coffee beans, soybeans, watermelon, corn, and many more.

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Thin-Film Measurement

Brimrose high speed AOTF-NIR Thin Film Analyzers perform laboratory tasks ON-LINE with extreme accuracy. To optimize the production process the instrument can be placed within production lines where accurate analytical monitoring of thin films or coatings is of importance. The instrument can be used for on-line specification verification, coating thickness measurement of single layer or multi-layer coatings on films or papers, etc.

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Measuring JP1 Fuel from Bladder Tanks on the Battlefield

Measuring JP1 Fuel from Bladder Tanks on the Battlefield

Oil/Gas Measurement

Qualification of Biodiesel is very important to both manufacturers and consumers, some of the important components to look at include Moisture, glycerides (mono, di, tri), and Fatty Acid Methyl Esters. It is essential to measure these components to ensure that the finished product is of the highest quality. Brimrose AOTF-NIR Spectrometers provide extremely fast measurements for all of your analytes simultaneously, providing better data trends for your refining process.

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Laboratory Accuracy

Brimrose AOTF-NIR spectrometers are extremely fast and have an excellent signal-to-noise ratio. As a lab device, settings are fully configurable to get the highest resolution and sensitivity for any application. Each order may be customized with any number of options or unique features like temperature controlled flow cells or adjustable lab stands.

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